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It's best known as a hallucinogenic club drug here in the U.S., but in many countries, ketamine has a more noble role.
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Currently, there's no quick fix for severe depression. Antidepressants usually take weeks to work, if they work at all. But patients who received experimental doses of ketamine — long used as an anesthetic, and an illegal club drug — report an astounding relief from their symptoms in less than a day.